Phytochemical Screening of Polyherbal Formulations used in Indian System of Medicine (AYUSH) for the Treatment of COVID-19 (SARS-CoV-2)

Dr. Senthil Kumar. B 1

8th WCPSDM.2021. APR.Published Online 18 APR 2021

Abstract : Ayurveda and Siddha are the two traditional Indian system of medicine that has been practiced widely many centuries. Both system of medicine has various Polyherbal formulations which were used to treat various diseases. Kabasura churana is a polyherbal formulation used in Siddha medicine to treat various types of fevers and flu along with respiratory complications. Maha Sudarshan churana is one of the Ayurvedic Polyherbal formulation traditionally used as antipyretic, anti-malarial and antiviral. The phytochemical screening of both polyherbal formulations contains in common the following ingredients with active compounds Zingiber officinale – Gingerol, Syzgium aromaticum –Aromatic, Piper nigrum – Piperine, Justicia adhatoda – Vasicine, Cuminum cyminum - Thymoquinone , Convolvulus pluricaulis - Convolamine and sitosterols, Solanum virginianum - Sitosterols, flavonoids and alkaloids Clerodendrum Serratum - Sitosterols and flavones, Piper longum – Piperine, Alpinia Galanga - Galanga esters, Trachyspermum ammi - Phenols and thymols, Hedyotis corymbosa - Flavonoids and anthraquinones, Glycyrrhiza glabra - Glycyrrhizin, Saccharum officinarum – Sugars, Curcuma longa – Curcuminoids, Picrorhiza kurrooa - Iridoid glycosides, apocynin, Andrographis paniculata – Andrographilide, Leucas cephalotes - Baicalin and flavones. Maha Sudarshan churana has Coriandrum sativum - flavonoids and Ocimum sanctum – Ursolic acid and tannins in addition to the above common ingredients, whereas the Kabasura churna has Syzgium aromaticum –aromatic in addition. The active compounds of Polyherbal formulations with their efficacy to inhibit SARS-CoV-2 virus will be discussed in the presentation.